The player controls Joel (voiced and motion-captured by Troy Baker) escorting the young Ellie (Ashley Johnson) across a post-apocalyptic United States that has been ravaged by infection. The player uses firearms, improvised weapons and stealth techniques to defend against hostile humans and zombie-like creatures infected by a mutated strain of the Cordyceps fungus.
https://www.youtube.com/watch?v=AaOWRvmtEFQ